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1

Activation of the precursor of gelatinase A/72 kda type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis

Masato Tokuraku, Hiroshi Sato, Sinya Murakami, Yasunori Okada, Yoh Watanabe, Motoharu Seiki

Journal:

International Journal of Cancer

Année:

1995

Langue:

english

Fichier:

PDF, 871 KB

english, 1995

2

Molecular mechanisms of regulation of HTLV-1 gene expression and its association with leukemogenesis

Yoshida, Mitsuaki, Inoue, Junichiro, Fujisawa, Junichi, Seiki, Motoharu

Journal:

Année:

1989

Langue:

english

Fichier:

PDF, 529 KB

english, 1989

3

Serum Monomeric Laminin-Î"2 as a Novel Biomarker for Hepatocellular Carcinoma

Kiyokawa, Hirofumi, Yasuda, Hiroshi, Okuse, Chiaki, Matsumoto, Nobuyuki, Yoshimura, Toru, Yoshida, Eisaku, Nakagawa, Masatoshi, Seiki, Motoharu, Koshikawa, Naohiko, Itoh, Fumio

Journal:

Gastroenterology

Année:

2017

Langue:

english

Fichier:

PDF, 487 KB

english, 2017

4

Unique Biological Activity and Potential Role of Monomeric Laminin-γ2 as a Novel Biomarker for Hepatocellular Carcinoma: A Review

Yasuda, Hiroshi, Nakagawa, Masatoshi, Kiyokawa, Hirofumi, Yoshida, Eisaku, Yoshimura, Toru, Koshikawa, Naohiko, Itoh, Fumio, Seiki, Motoharu

Journal:

International Journal of Molecular Sciences

Année:

2019

Fichier:

PDF, 11.11 MB

2019

5

Inhibition of metastasis in human gastric cancer cells transfected with tissue inhibitor of metalloproteinase 1 gene in nude mice

Michio Watanabe, Yutaka Takahashi, Takahito Ohta, Masayashi Mai, Takuma Sasaki, Motoharu Seiki

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 511 KB

english, 1996

6

Increased expression of membrane type 1-matrix metalloproteinase in head and neck carcinoma

Tomokazu Yoshizaki, Hiroshi Sato, Yumiko Maruyama, Shigeyuki Murono, Mitsuru Furukawa, Chang-Soo Park, Motoharu Seiki

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 117 KB

english, 1997

7

Enhanced production of matrix metalloproteinases and activation of matrix metalloproteinase 2 (gelatinase A) in human gastric carcinomas

Hidehiro Nomura, Noboru Fujimoto, Motoharu Seiki, Masayoshi Mai, Yasunori Okada

Journal:

International Journal of Cancer

Année:

1996

Langue:

english

Fichier:

PDF, 831 KB

english, 1996

8

Dual over-expression pattern of membrane-type metalloproteinase-1 in cancer and stromal cells in human gastrointestinal carcinoma revealed by in situ hybridization and immunoelectron microscopy

Haruo Ohtani, Hozumi Motohashi, Hiroshi Sato, Motoharu Seiki, Hiroshi Nagura

Journal:

International Journal of Cancer

Année:

1996

Langue:

english

Fichier:

PDF, 936 KB

english, 1996

9

A BALB/c 3T3-transformed cell line suitable for transfection assay of metastasis-inducing genes

Masaaki Tatsuka, Takahide Ota, Masayo Maeda, Morimasa Wada, Nobuyuki Yamagishi, Shun'ichiro Taniguchi, Motoharu Seiki, Shizuo Odashima

Journal:

International Journal of Cancer

Année:

1997

Langue:

english

Fichier:

PDF, 101 KB

english, 1997

10

The Ets-1 and Ets-2 transcription factors activate the promoters for invasion-associated urokinase and collagenase genes in response to epidermal growth factor

Tetsuya Watabe, Koichi Yoshida, Masanobu Shindoh, Mitsunori Kaya, Keiko Fujikawa, Hiroshi Sato, Motoharu Seiki, Seiichi Ishii, Kei Fujinaga

Journal:

International Journal of Cancer

Année:

1998

Langue:

english

Fichier:

PDF, 177 KB

english, 1998

11

Regulation of matrix metalloproteinase-2 (MMP-2) by hepatocyte growth factor/scatter factor (HGF/SF) in human glioma cells: HGF/SF enhances MMP-2 expression and activation accompanying up-regulation of membrane type-1 MMP

Ryouichi Hamasuna, Hiroaki Kataoka, Takuzou Moriyama, Hiroshi Itoh, Motoharu Seiki, Masashi Koono

Journal:

International Journal of Cancer

Année:

1999

Langue:

english

Fichier:

PDF, 292 KB

english, 1999

12

Different metastatic potentials of ras- and src-transformed BALB/c 3T3 A31 variant cells

Masaaki Tatsuka, Takahide Ota, Nobuyuki Yamagishi, Yasunari Kashihara, Morimasa Wada, Naoki Matsuda, Hiromi Mitsui, Motoharu Seiki, Shizuo Odashima

Journal:

Molecular Carcinogenesis

Année:

1996

Langue:

english

Fichier:

PDF, 887 KB

english, 1996

13

Significant correlation of monocyte chemoattractant protein-1 expression with neovascularization and progression of breast carcinoma

Hisashi Saji, Morio Koike, Takao Yamori, Shigehira Saji, Motoharu Seiki, Kouji Matsushima, Masakazu Toi

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 191 KB

english, 2001

14

Membrane type 1 matrix metalloproteinase is a crucial promoter of synovial invasion in human rheumatoid arthritis

Mary-Clare Miller, Hugh B. Manning, Abhilash Jain, Linda Troeberg, Jayesh Dudhia, David Essex, Ann Sandison, Motoharu Seiki, Jagdeep Nanchahal, Hideaki Nagase, Yoshifumi Itoh

Journal:

Arthritis & Rheumatism

Année:

2009

Langue:

english

Fichier:

PDF, 782 KB

english, 2009

15

ChemInform Abstract: Ancorinosides B-D, Inhibitors of Membrane Type 1 Matrix Metalloproteinase (MT1-MMP), from the Marine Sponge Penares sollasi Thiele

Masaki Fujita, Yoichi Nakao, Shigeki Matsunaga, Motoharu Seiki, Yoshifumi Itoh, Rob W. M. van Soest, Nobuhiro Fusetani

Journal:

Année:

2001

Fichier:

PDF, 26 KB

2001

16

ChemInform Abstract: Bioactive Marine Metabolites. Part 107. Isolation and Structure Elucidation of Two Phosphorylated Sterol Sulfates, MT1-MMP Inhibitors from a Marine Sponge Cribrochalina sp.: Revision of the Structures of Haplosamates A and B.

Masaki Fujita, Yoichi Nakao, Shigeki Matsunaga, Motoharu Seiki, Yoshifumi Itoh, Rob W. M. van Soest, Markus Heubes, D. John Faulkner, Nobuhiro Fusetani

Journal:

Année:

2001

Fichier:

PDF, 30 KB

2001

17

Increased expression of matrix metalloproteinase-II in experimental liver fibrosis in rats

Terumi Takahara, Kei Furui, Jun Funaki, Yoshihide Nakayama, Hiroyuki Itoh, Chiharu Miyabayashi, Hiroshi Sato, Motoharu Seiki, Akira Ooshima, Akiharu Watanabe

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 1.10 MB

english, 1995

18

lymphoma type adult T-cell leukemia—a clinicopathologic study of HTLV related T-cell type malignant lymphoma

Kazunari Yamaguchi, Ritsuko Yoshioka, Tetsuyuki Kiyokawa, Motoharu Seiki, Mitsuaki Yoshida, Kiyoshi Takatsuki

Journal:

Hematological Oncology

Année:

1986

Langue:

english

Fichier:

PDF, 590 KB

english, 1986

19

Comparison of autocrine mechanisms promoting motility in two metastatic cell lines: Human melanoma and ras-transfected NIH3T3 cells

Motoharu Seiki, Hiroshi Sato, Lance A. Liotta, Elliott Schiffmann

Journal:

International Journal of Cancer

Année:

1991

Langue:

english

Fichier:

PDF, 437 KB

english, 1991

20

Expression of type-IV collagenases in human tumor cell lines that can form liver colonies in chick embryos

Yuri Tsuchiya, Yoshio Endo, Hiroshi Sato, Yasunori Okada, Masayoshi Mai, Takuma Sasaki, Motoharu Seiki

Journal:

International Journal of Cancer

Année:

1994

Langue:

english

Fichier:

PDF, 2.11 MB

english, 1994

21

MT1-MMP: A potent modifier of pericellular microenvironment

Yoshifumi Itoh, Motoharu Seiki

Journal:

Journal of Cellular Physiology

Année:

2006

Langue:

english

Fichier:

PDF, 234 KB

english, 2006

22

Adsorption Characteristics of Bisphenol A onto Carbonaceous Materials Produced from Wood Chips as Organic Waste

Akio Nakanishi, Motoharu Tamai, Naohito Kawasaki, Takeo Nakamura, Seiki Tanada

Journal:

Journal of Colloid and Interface Science

Année:

2002

Langue:

english

Fichier:

PDF, 201 KB

english, 2002

23

Characterization of Water Adsorption onto Carbonaceous Materials Produced from Food Wastes

Akio Nakanishi, Motoharu Tamai, Naohito Kawasaki, Takeo Nakamura, Mamiko Araki, Seiki Tanada

Journal:

Journal of Colloid and Interface Science

Année:

2002

Langue:

english

Fichier:

PDF, 93 KB

english, 2002

24

Ancorinosides B–D, inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP), from the marine sponge Penares sollasi Thiele

Masaki Fujita, Yoichi Nakao, Shigeki Matsunaga, Motoharu Seiki, Yoshifumi Itoh, Rob W.M van Soest, Nobuhiro Fusetani

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 124 KB

english, 2001

25

Isolation and structure elucidation of two phosphorylated sterol sulfates, MT1-MMP inhibitors from a marine sponge Cribrochalina sp.: revision of the structures of haplosamates A and B

Masaki Fujita, Yoichi Nakao, Shigeki Matsunaga, Motoharu Seiki, Yoshifumi Itoh, Rob W.M van Soest, Markus Heubes, D.John Faulkner, Nobuhiro Fusetani

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 220 KB

english, 2001

26

Flow injection analysis for measurement of activity of matrix metalloproteinase-7 (MMP-7)

Michiyasu Itoh, Mamoru Osaki, Tadashige Chiba, Kazuto Masuda, Toshifumi Akizawa, Masanori Yoshioka, Motoharu Seiki

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Année:

1997

Langue:

english

Fichier:

PDF, 706 KB

english, 1997

27

Activation of pro-MMP-2 mediated by MT1-MMP in human salivary gland carcinomas: possible regulation of pro-MMP-2 activation by TIMP-2

Kaori Kayano, Taketoshi Shimada, Takashi Shinomiya, Shigeru Nakai, Yasuo Hisa, Takanori Aoki, Motoharu Seiki, Yasunori Okada

Journal:

The Journal of Pathology

Année:

2004

Langue:

english

Fichier:

PDF, 511 KB

english, 2004

28

Structure and function of the region of the replication origin of theBacillus subtilischromosome

Motoharu Seiki, Naotake Ogasawara, Hiroshi Yoshikawa

Journal:

Molecular Genetics and Genomics

Année:

1981

Langue:

english

Fichier:

PDF, 791 KB

english, 1981

29

Structure and function of the region of the replication origin of theBacillus subtilischromosome

Motoharu Seiki, Naotake Ogasawara, Hiroshi Yoshikawa

Journal:

Molecular Genetics and Genomics

Année:

1981

Langue:

english

Fichier:

PDF, 742 KB

english, 1981

30

Initiation of DNA replication inBacillus subtilis

Hiroshi Yoshikawa, Naotake Ogasawara, Motoharu Seiki

Journal:

Molecular Genetics and Genomics

Année:

1980

Langue:

english

Fichier:

PDF, 760 KB

english, 1980

31

Initiation of DNA replication inBacillus subtilis

Naotake Ogasawara, Motoharu Seiki, Hiroshi Yoshikawa

Journal:

Molecular Genetics and Genomics

Année:

1981

Langue:

english

Fichier:

PDF, 1.09 MB

english, 1981

32

Expression and localization of membrane-type-1 matrix metalloproteinase, CD 44, and laminin-5γ2 chain during colorectal carcinoma tumor progression

Shinji Murai, Toshifumi Umemiya, Motoharu Seiki, Kenichi Harigaya

Journal:

Virchows Archiv

Année:

2004

Langue:

english

Fichier:

PDF, 727 KB

english, 2004

33

Differentiation-dependent expression of gelatinase B/matrix metalloproteinase-9 in trophoblast cells

T. J. Peters, Andrea Albieri, Estela Bevilacqua, Belinda M. Chapman, L. H. Crane, G. P. Hamlin, Motoharu Seiki, M. J. Soares

Journal:

Cell and Tissue Research

Année:

1999

Langue:

english

Fichier:

PDF, 138 KB

english, 1999

34

Impaired alveolization in mice deficient in membrane-type matrix metalloproteinase 1 (MT1-MMP)

Kazuharu Irie, Kiyoshi Komori, Motoharu Seiki, Eichi Tsuruga, Yasunori Sakakura, Tohru Kaku, Toshihiko Yajima

Journal:

Medical Molecular Morphology

Année:

2005

Langue:

english

Fichier:

PDF, 504 KB

english, 2005

35

Homophilic complex formation is prerequisite for MT1-MMP to degrade type-I collagen on the cell surface

Yoshifumi Itoh, Noriko Ito, Hideaki Nagase, Motoharu Seiki

Journal:

International Journal of Experimental Pathology

Année:

2004

Langue:

english

Fichier:

PDF, 372 KB

english, 2004

36

CELL-LINE SPECIFIC ACTIVATION OF SV40 TRANSCRIPTIONAL ENHANCER BY p40tax OF HTLV-1

Jun-ichi Fujisawa, Motoharu Seiki, Masami Toita, Shoichiro Miyatake, Ken-ichi Arai, Mitsuaki Yoshida

Journal:

Année:

1988

Fichier:

PDF, 224 KB

1988

37

Experimental Metastasis of Oncogene-transformed NIH 3T3 Cells in Chick Embryo

Yoshio Endo, Motoharu Seiki, Hiroyuki Uchida, Mika Noguchi, Yuri Kida, Hiroshi Sato, Masayoshi Mai, Takuma Sasaki

Journal:

Année:

1992

Fichier:

PDF, 457 KB

1992

38

Significance of Membrane Type 1 Matrix Metalloproteinase Expression in Breast Cancer

Shinsuke Ishigaki, Masakazu Toi, Takayuki Ueno, Hiroshi Matsumoto, Mariko Muta, Morio Koike, Motoharu Seiki

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 485 KB

english, 1999

39

Shedding of Membrane Type 1 Matrix Metalloproteinase in a Human Breast Carcinoma Cell Line

Takeshi Harayama, Eiko Ohuchi, Takanori Aoki, Hiroshi Sato, Motoharu Seiki, Yasunori Okada

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 1.60 MB

english, 1999

40

Roles of pericellular proteolysis by membrane type-1 matrix metalloproteinase in cancer invasion and angiogenesis

Motoharu Seiki, Ikuo Yana

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 258 KB

english, 2003

41

High throughput analysis of proteins associating with a proinvasive MT1-MMP in human malignant melanoma A375 cells

Taizo Tomari, Naohiko Koshikawa, Takayuki Uematsu, Takashi Shinkawa, Daisuke Hoshino, Nagayasu Egawa, Toshiaki Isobe, Motoharu Seiki

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2009

42

Proteolytic activation of heparin-binding EGF-like growth factor by membrane-type matrix metalloproteinase-1 in ovarian carcinoma cells

Naohiko Koshikawa, Hiroto Mizushima, Tomoko Minegishi, Fuyuki Eguchi, Fusanori Yotsumoto, Kazuki Nabeshima, Shingo Miyamoto, Eisuke Mekada, Motoharu Seiki

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 611 KB

english, 2011

43

Membrane-type 1 matrix metalloproteinase cytoplasmic tail binding protein-1 (MTCBP-1) acts as an eukaryotic aci-reductone dioxygenase (ARD) in the methionine salvage pathway

Wakako Hirano, Isamu Gotoh, Takamasa Uekita, Motoharu Seiki

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 322 KB

english, 2005

44

Regulated nucleo-cytoplasmic shuttling of human aci-reductone dioxygenase (hADI1) and its potential role in mRNA processing

Isamu Gotoh, Takamasa Uekita, Motoharu Seiki

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 359 KB

english, 2007

45

Establishment of an MT4-MMP-deficient mouse strain representing an efficient tracking system for MT4-MMP/MMP-17 expression in vivo using β-galactosidase

Akiko Rikimaru, Kiyoshi Komori, Takeharu Sakamoto, Hirotake Ichise, Nobuaki Yoshida, Ikuo Yana, Motoharu Seiki

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 448 KB

english, 2007

46

Cytoplasmic tail of MT1-MMP regulates macrophage motility independently from its protease activity

Takeharu Sakamoto, Motoharu Seiki

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2009

47

Identification of CD44 as a cell surface marker for Müller glia precursor cells

Toru Shinoe, Hiroshi Kuribayashi, Hideyuki Saya, Motoharu Seiki, Hiroyuki Aburatani, Sumiko Watanabe

Journal:

Journal of Neurochemistry

Année:

2010

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2010

48

Membrane-type matrix metalloproteinases

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 795 KB

english, 1999

49

Development and Application of a Microplate Assay Method for the Mass Screening of MMP Inhibitors

TOSHIFUMI AKIZAWA, TAKAYUKI URATANI, MOTOMI MATSUKAWA, ASUKA KUNIMATSU, YUKO ITO, MICHIYASU ITOH, YUKIO OHSHIBA, MASASHI YAMADA, MOTOHARU SEIKI

Journal:

Annals of the New York Academy of Sciences

Année:

1999

Langue:

english

Fichier:

PDF, 608 KB

english, 1999

50

Transient Increase of Intracellular cAMP by Heat Shock Initiates the Suppression of MT1-MMP Production in Tumor Cells

YASUNOBU SAWAJI, TAKASHI SATO, MOTOHARU SEIKI, AKIRA ITO

Journal:

Annals of the New York Academy of Sciences

Année:

1999

Langue:

english

Fichier:

PDF, 420 KB

english, 1999